Idiopathic subglottic stenosis: change of therapeutic paradigms?
09-13, 09:30–10:00 (Europe/Istanbul), Laryngology 2

<p>Background</p> <p>Subglottic stenosis (SGS) of uncertain aetiology including idiopathic SGS (iSGS) and vasculitis-associated SGS (vSGS, classically granulomatosis with polyangiitis)—remains a therapeutic challenge. Restenosis commonly follows office based interventions, operating room (OR) procedures, and open neck surgery, yet definitive treatment guidelines are still lacking.</p> <p>Objective</p> <p>Compare long-term outcomes of office based, OR treatment and open neck procedures in uncertain-etiology SGS and use those data to craft a pragmatic flow chart that standardises work-up, treatment decision making.</p> <p>Description</p> <p>A retrospective institutional cohort of patients with idiopathic or vasculitic subglottic stenosis (SGS) will be analysed. Outcomes will include decannulation rate, number of operative and office-based interventions, complication rate and management.</p> <p>Outcomes</p> <p>Among 200 patients undergoing CTR, 15 had idiopathic SGS (all female) and 5 vasculitis SGS with a 100% decannulation rate. Postoperative issues included granulomas (n=6) managed with oral corticosteroids in 3 cases, and additional interventions—radial incision with intralesional corticosteroids, SILSI in others), and 1 case of restenosis managed with radial incision and keel placement. In the endoscopic group (N=24), 19 had iSGS (18 female, 1 male) and 2 vSGS (all female) undergoing a total of 33 OR procedures (including radial incisions, balloon dilatation, steroid injection, and synechia lysis. Three patients received T-tube placement and one required keel) and 5 office-based steroid injections (SILSI). Based on these findings, we will propose a structured, evidence-informed flow chart to guide clinical decision-making in the management of SGS.</p>

<p>Purpose of your Proposal:</p> <p>Subglottic stenosis (SGS) of uncertain aetiology including idiopathic SGS and vasculitis-associated SGS remains a therapeutic challenge. Both, share a propensity for restenosis after airway expansion, yet no consensus management algorithm exists. Therefore, based on our findings we propose a structured flow chart streamlining decision making SGS treatment.</p>
Speaker Speaker
<p>I graduated as a medical doctor from the University Our Lady Of Good Counsel, Tirana, Albania, in July 2023. My journey in the field of medicine has been characterized by a series of experiences and internships, particularly in the Head and Neck specialty, commencing with a two-year tenure at the American Hospital in Tirana.</p> <p>My enriching experiences continued with three weeks spent at Policlinico Tor Vergata, Rome, in May 2022, followed by an equally enlightening period of three weeks at Ospedale Civile, Brescia.</p> <p>I obtained my medical license from Policlinico Tor Vergata, Rome, between October and December 2023. During this period, I completed a two-month internship at the ENT department of Istituto Nazionale Tumori Regina Elena (IFO).</p> <p>I am currently a resident in Head and Neck Surgery in Genoa, where I continue to deepen my clinical expertise.</p> <p>Furthermore, I've actively contributed to the academic sphere by co-authoring abstracts and articles selected for publication and presentation at conferences held in Greece and Rome, reflecting my dedication to continuous learning and sharing insights with the international medical community.</p>
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