09-13, 10:45–11:15 (Europe/Istanbul), Audiology 2
Sudden sensorineural hearing loss (SSNHL) continues to present major diagnostic and therapeutic challenges, despite decades of research. While most current guidelines focus on empirical treatments such as systemic or intratympanic steroids, recent advances in diagnostics have raised fundamental questions about overlooked causes—especially Perilymphatic Fistula (PLF).
This keynote lecture will introduce a paradigm shift in the way we understand and treat SSNHL, with a focus on the following key topics:
An overview of recent evidence from clinical trials involving steroids, antivirals, and regenerative therapies
The emerging role of biomarkers and imaging in identifying subgroups and predicting prognosis
Re-examining PLF as a real and often unrecognized etiology of SSNHL
Introduction of MiTT-PLF-S: a newly developed minimally invasive trans-tympanic PLF repair technique using fibrin glue, with clinical data and case outcomes
Notably, MiTT-PLF-S has shown hearing improvement even in patients beyond the traditional 28-day treatment window, suggesting its potential value for delayed cases
Discussion on how endotype-based approaches can enhance early intervention and precision treatment in SSNHL
Insights gained from over 1,500 cases of Cochlin-tomoprotein (CTP) testing, which has been officially Japanese FDA approved and reimbursed as a diagnostic tool in Japan. These nationwide results have helped shape current clinical strategies and deepen understanding of PLF-related hearing loss.
The speaker has been appointed as the chair of the newly established Bárány Society Diagnostic Criteria Committee for PLF, and will also share insights from ongoing international discussions shaping the future framework of PLF diagnosis.
The lecture will challenge traditional frameworks and propose a new clinical pathway that integrates mechanism-based diagnosis, novel surgical options, and personalized therapy.
Target Audience: Otologists, neurotologists, ENT surgeons, audiologists, and clinicians involved in hearing loss diagnosis and treatment
- Helpful Listening Tools
- Artıfıcıal intelligence in medicine and technological tools for neurosciences
- Audiology Education; What does General Audiologist Mean?
- Mirko Tos Ear&Hearing Research and Innovation
- Understanding oto-acoustic emissions – an easy and intuitive introduction
- The Effect of Cochlear Implants on Cognitive Function in Older Adults
- Modern approaches to the pediatric amplification
- Relationship between normal or impaired hearing and accurate singing in singers of all ages
Current Roles
Director, Clinical Research Center, Saitama Medical University (2020 – Present)
Director, Public Relations Office, Saitama Medical University (2022 – 2025)
Professor and Chairman, Department of Otorhinolaryngology, Saitama Medical University (2016 – Present)
Professional Experience
Vice President, Saitama Medical University Hospital (2018 – 2022)
Professor, Department of Otorhinolaryngology, Saitama Medical University, Saitama, Japan (2011 – 2016)
Associate Professor, Department of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan (2007 – 2011)
Visiting Fellow, National Institutes of Health (NIH), Bethesda, MD, USA (1992 – 1995)
Leadership
Board Member, Japanese Society of Otorhinolaryngology (2022 – Present)
Board Member, Japanese Otological Society (2018 – 2024)
Board Member, Japanese Society for Equilibrium Research (2014 – 2019, 2021 – 2022, 2025-)
Criteria head, Barany Society Committee for Establishing Diagnostic Criteria of Perilymphatic Fistula