Description and Background: Transoral laser microsurgery (TLM) is a well-established organ-preserving treatment modality for selected laryngeal cancers, offering excellent oncologic outcomes with favorable functional results when applied with appropriate patient selection and meticulous surgical technique. This instructional course will provide a practical and step-by-step overview of transoral laser surgery for supraglottic and glottic laryngeal cancers, focusing on indication criteria, exposure strategies, laser settings, and resection techniques. Key technical aspects such as en bloc versus multi-bloc resection, margin assessment, management of close or positive margins, and decision-making in cases with challenging exposure will be discussed. Surgical videos and representative clinical cases will be used to demonstrate operative nuances, common pitfalls, and complication management, including bleeding, airway compromise, and aspiration. The course will also address the integration of TLM into multidisciplinary treatment planning, including the role of neck management, adjuvant therapy, and follow-up strategies.

Outcome Objectives: At the end of this course, participants will be able to:

• Identify appropriate indications and contraindications for TLM in laryngeal cancer

• Understand key technical steps and laser safety principles

• Apply oncologic concepts of margin control in transoral resections

• Recognize and avoid common technical and oncologic pitfalls

• Integrate TLM into a multidisciplinary treatment strategy for laryngeal cancer