Component-Resolved Diagnosis for Otorhinolaryngologists
09-11, 15:30–16:00 (Europe/Istanbul), Rhinology 5 + Allergy (ICC - B2 level YILDIZ 1)

<p>Component-resolved diagnosis (CRD) has emerged as a valuable complement to conventional allergy testing by identifying specific allergenic molecules rather than whole allergen extracts. For otorhinolaryngologists managing patients with allergic rhinitis, polysensitization, oral allergy syndrome, or uncertain clinical–test correlations, CRD can provide a more precise understanding of the patient’s sensitization profile.</p> <p>This instructional course will introduce the basic principles of molecular allergology and demonstrate how CRD can be incorporated into everyday rhinology practice. Particular emphasis will be placed on distinguishing genuine primary sensitization from cross-reactivity, recognizing major allergen components and panallergens, and interpreting sensitization to profilins, polcalcins, lipid transfer proteins, tropomyosins, and cross-reactive carbohydrate determinants. Clinically relevant examples involving grass, tree and weed pollens, house dust mites, moulds, and selected food allergens will be discussed.</p> <p>Participants will learn how molecular findings may clarify apparently conflicting skin-prick test or specific IgE results, identify the allergen sources most likely to be responsible for symptoms, and improve the selection of allergens for allergen immunotherapy. The course will also address the limitations of CRD, including the distinction between sensitization and clinically relevant allergy, the need to interpret results within the context of exposure and symptom history, and situations in which molecular testing is unlikely to alter management.</p> <p>Through case-based discussions, the course aims to provide otorhinolaryngologists with a practical framework for requesting, interpreting, and applying CRD appropriately. At the end of the session, participants should be able to use molecular allergy testing more confidently while avoiding both overdiagnosis and unnecessary allergen immunotherapy.</p>
<p>The purpose of this course is to provide otorhinolaryngologists with a practical and clinically oriented understanding of component-resolved diagnosis in the evaluation of allergic rhinitis. The course aims to improve participants’ ability to distinguish genuine sensitization from cross-reactivity, interpret molecular allergy test results, correlate laboratory findings with clinical history, and select clinically relevant allergens for immunotherapy. By using case-based examples, the course will support more accurate diagnosis, reduce unnecessary testing and inappropriate immunotherapy, and facilitate the integration of molecular allergology into routine rhinology practice.</p>
Session Chair Session Chair
Nurcan Yurtsever Kum
Speaker Speaker
Müge Özcan
Müge Özcan
<p>Prof. Dr. Müge Özcan was born in Ankara in 1967. She completed her primary, secondary, and high school education in Tarsus. She graduated as the top student from Cengiz Topel Middle School and Tarsus High School.</p> <p>Prof. Dr. Müge Özcan began her studies at Hacettepe University's English Faculty of Medicine in 1984, graduating first in her preparatory year. In 1990, she received the Prof. Dr. M. Şeref Zileli Award for Successful Student of the Year from Hacettepe University Faculty of Medicine. She graduated from Hacettepe University's English Faculty of Medicine in 1991.</p> <p>Prof. Dr. Müge Özcan completed her ENT specialization training at Ankara Numune Hospital's 1st ENT Clinic in 1996. She worked as an ENT Specialist at Ankara Numune Training and Research Hospital from 1996 to 1999, and as the Chief Assistant of the ENT Clinic from 1999 to 2003. Prof. Dr. Müge Özcan, who became an Associate Professor of ENT in 2003 and was appointed Assistant Chief of the 1st ENT Clinic at Ankara Numune Training and Research Hospital, became a Training Officer in the ENT Clinic at the same hospital in 2011. In 2016, she was appointed Professor at the ENT Clinic of Hitit University Faculty of Medicine, and continued her duties until 2017, alternating between Hitit University Faculty of Medicine and Ankara Numune Training and Research Hospital. In 2017, she was appointed Professor at Hamidiye Faculty of Medicine, Health Sciences University, and assigned to Ankara Numune Training and Research Hospital. In 2018, she became the Training and Administrative Head of the ENT Clinic at the same hospital, continuing in this role until Ankara Numune Training and Research Hospital was closed in 2019.</p> <p>In 2019, she was assigned as a Training Officer at the ENT Clinic of Ankara City Hospital by Health Sciences University. She retired voluntarily in 2020. Prof. Dr. Müge Özcan continues her profession in her private practice.</p>
This speaker also appears in:
Nurcan Yurtsever Kum
<p>Assoc. Prof. Nurcan Yurtsever Kum is a distinguished academician in Bilkent City Hospital, Ankara, Türkiye.</p>