Daniel Lee

Daniel Lee is the Ansin Foundation Chair in Otolaryngology at the Massachusetts Eye and Ear Infirmary (MEEI) and Harvard Medical School. He is Director of Pediatric Otology and Neurotology, Program Director of the Harvard Neurotology Fellowship and Director of International Patient Services in the Department of Otolaryngology at MEEI. Dr. Lee's funded basic and translational research group seeks to answer fundamental questions about central auditory processing and how to improve auditory brainstem implant outcomes for patients with Neurofibromatosis Type 2 (NF2). He has developed an international center for the care of patients with superior canal dehiscence syndrome, endoscopic ear surgery, and complex cochlear and auditory brainstem implant surgery. He serves on the scientific advisory board for Skylark Bio, a Cambridge, Massachusetts-based company focusing on gene therapy for children with GJB2 related congenital hearing loss.


Sessions

09-10
10:45
30min
Endoscopic ear surgery
Daniel Lee
Otology/Neurotology
Otology 4
09-12
11:15
90min
Complications in CI
Daniel Lee, Abdulmonem H. Al Shaikh, Dan Cristian Gheorghe, Daniel Kaplan, Ahmad Daneshi, Ossama Hamid, Enis Alpin Güneri, Chunfu Dai

Panel Presentation Complications in CI

Cochlear Implants and implantable devices
Hearing Implant 1
09-12
14:00
60min
Optogenetic Hearing Restoration
Daniel Lee, Tobias Moser, Kathrin Kusch, Rachael Richardson

This session introduces optogenetic hearing restoration, a novel strategy using light-sensitive proteins (opsins) to enable precise, optical stimulation of auditory neurons. This approach bypasses damaged hair cells to directly activate the auditory nerve with light.

Outcome Objectives Participants will be able to:

  1. Explain the basic mechanism of optogenetic stimulation in the cochlea.

  2. Compare the potential benefits of optogenetics over traditional cochlear implants.

  3. Identify key challenges for clinical translation.

Background Cochlear implants provide limited spectral resolution. Optogenetics offers a revolutionary approach to potentially restore high-fidelity hearing by enabling more precise, frequency-specific activation of the auditory nerve than is possible with electrical stimulation.

Kaynaklar

Transverse activities (Innovation, Basic Research, Education)
Otology 4