Odontogenic Sinusitis: from Teeth to the Sinuses and Beyond

Description: This session introduces the clinical and scientific applications of large language models (LLMs) in otolaryngology. Attendees will explore how tools like ChatGPT can transform diagnostics, research methodologies, and patient communication within our specialty. Drawing on original research and practical examples, the presentation unveils innovative case studies that illustrate both the promising capabilities and inherent challenges of integrating AI in clinical practice. An engaging “pearls and pitfalls” segment will stimulate critical discussion on best practices and ethical considerations.

Outcome Objectives: By the end of the session, participants will be able to:

- Analyze the role of LLMs in enhancing clinical decision-making in otolaryngology.
- Demonstrate the practical use of ChatGPT for generating research insights and supporting patient care.
- Examine potential challenges and limitations associated with AI integration.
- Explain ethical and practical guidelines for incorporating LLMs into routine practice.

Structure of the Session: The presentation is structured in three segments: an introductory overview of LLM technology, an interactive demonstration featuring case studies and research findings, and a facilitated discussion addressing both the advantages and the pitfalls of AI applications in otolaryngology.

1. Background: Vaira LA, Lechien JR, […] Saibene AM, et al. Evaluating AI-Generated informed consent documents in oral surgery: A comparative study of ChatGPT-4, Bard gemini advanced, and human-written consents. J Craniomaxillofac Surg. 2025 Jan;53(1):18-23. doi: 10.1016/j.jcms.2024.10.002. Epub 2024 Oct 26. PMID: 39490345.
2. Lorenzi A, Pugliese G, […] Saibene AM. Reliability of large language models for advanced head and neck malignancies management: a comparison between ChatGPT 4 and Gemini Advanced. Eur Arch Otorhinolaryngol. 2024 Sep;281(9):5001-5006. doi: 10.1007/s00405-024-08746-2. Epub 2024 May 25. PMID: 38795148; PMCID: PMC11392976.
3. Maniaci A, Saibene AM, […] Cocuzza S. Is generative pre-trained transformer artificial intelligence (Chat-GPT) a reliable tool for guidelines synthesis? A preliminary evaluation for biologic CRSwNP therapy. Eur Arch Otorhinolaryngol. 2024 Apr;281(4):2167-2173. doi: 10.1007/s00405-024-08464-9. Epub 2024 Feb 8. PMID: 38329526.
4. Saibene AM, Allevi F, […], Craig JR. Reliability of large language models in managing odontogenic sinusitis clinical scenarios: a preliminary multidisciplinary evaluation. Eur Arch Otorhinolaryngol. 2024 Apr;281(4):1835-1841. doi: 10.1007/s00405-023-08372-4. Epub 2024 Jan 8. PMID: 38189967; PMCID: PMC10943141.
5. Pugliese G, Maccari A, […] Saibene AM. Are artificial intelligence large language models a reliable tool for difficult differential diagnosis? An a posteriori analysis of a peculiar case of necrotizing otitis externa. Clin Case Rep. 2023 Sep 19;11(9):e7933. doi: 10.1002/ccr3.7933. PMID: 37736475; PMCID: PMC10509342.

In this symposia, the audience will get an up to date overview of the current state of the art treatment of children with CF, including new CFTR modulator therapy, ototoxicity screening, indications for sinus surgery

- Sinonasal manifestations of CF in children - prof Vroegop
- Ototoxicity and otitis media in children with CF - prof. Van der Poel
- CFTR Modulators - an update - prof Van Hoorenbeeck
- Gaps in literature and future outlook - prof Saibene

The topic Pott’s puffy tumor is suitable for a round table or an instructional course.

The session will focus on diagnostic considerations, non-surgical treatment options, surgical treatment options, and multidisciplinary management of Pott’s puffy tumor.

Since Pott’s puffy tumor patients can be children, adolescents and adults, this could be in the Pediatric or Rhinology track