Professor Mercante is involved in several National and International Clinical Research Groups as Coordinator and Principal Investigator, with the aim to promote a multidisciplinary approach to the Head and Neck Cancer Patient in order to reach an early diagnosis and to offer a personalized treatment, also focusing on the quality of life of the patient.

His clinical activities are mainly devoted to Head and Neck surgery, particularly to thyroid and parathyroid glands surgery, minimally invasive approaches, robotic surgery and open neck surgery for laryngeal and pharyngeal cancers, major and minor salivary glands tumors, reconstructive head and neck surgery with free and pedunculated flaps, as well as to the treatment of functional pathologies through phonosurgery, endoscopic nasal and sinus surgery, sleep apnea surgery and pediatric ENT surgery.